The role of autonomic responses to cardiopulmonary exercise testing in predicting surgical outcome in non-cardiac surgical patients

Not Applicable

Completed

• Conditions: Topic: Generic Health Relevance and Cross Cutting Themes; Subtopic: Generic Health Relevance (all Subtopics); Disease: Surgery, Anaesthetics; Surgery

• Registration Number: ISRCTN88456378
• Lead Sponsor: niversity College London Hospitals NHS Foundation Trust & University College London (UK)

Brief Summary

2017 results in https://www.ncbi.nlm.nih.gov/pubmed/28974075 (added 22/01/2019) 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29397143 (added 22/01/2019) 2019 secondary analysis in https://www.ncbi.nlm.nih.gov/pubmed/31433825 (added 04/03/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-08-22
• Study Completion: 2015-03-01
• Last Update Posted: 30 March 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 778

Inclusion Criteria

1. All surgical patients referred for cardiopulmonary exercise testing preoperatively undergoing major non-cardiac surgery
2. Aged 18-95 years

Exclusion Criteria

1. History of exercise-induced angioedema
2. Pregnancy
3. Any contraindication to cardiopulmonary exercise testing (as outlined by American Association of Anaesthesia)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post-operative morbidity survey; Timepoint(s): Preop, postop days 3, 7, 14

Secondary Outcome Measures

Name	Time	Method
ot provided at time of registration