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Evaluation of the Role of Latent Toxoplasmosis in Female Patients With Active Acne Vulgaris

Not Applicable
Not yet recruiting
Conditions
Acne Vulgaris
Toxoplasmosis
Interventions
Diagnostic Test: Free testosterone levels and toxoplasma igG
Registration Number
NCT05783778
Lead Sponsor
Sohag University
Brief Summary

Acne vulgaris is one if the most common chronic inflammatory skin disorders.Acne is characterized by forming of inflammatory and non inflammatory lesions mainly on the Face,neck,arms, upper trunk and back

Detailed Description

One of the hidden hormonal imbalance is Toxoplasma infection.Toxoplasmosis is a zoonotic infection the definite host is feline whereas human and other warm blooded animals are intermediate host . Endocrine alterations occuring during toxoplasmosis can be a hidden cause of acne vulgaris

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
Female
Target Recruitment
200
Inclusion Criteria
  • Female patients with active acne vulgaris
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Exclusion Criteria
  • Patients with history of hormonal treatment Patients received anti toxoplasma therapy Patients with dermatological diseases caused by hormonal disturbances Pregnant and lactating patients
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Toxoplasmosis seropositive female patients with active acne vulgarisFree testosterone levels and toxoplasma igG-
Toxoplasmosis seronegative in female patients with active acne vulgarisFree testosterone levels and toxoplasma igG-
Primary Outcome Measures
NameTimeMethod
Measuring Toxoplasma igG and free testosterone in acne vulgaris patients and controlsOne month

Detect if the toxoplasma latent infection can be associated with disease severity and hormonal disturbances in acne vulgaris female patients

Secondary Outcome Measures
NameTimeMethod
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