Evaluation of the Role of Latent Toxoplasmosis in Female Patients With Active Acne Vulgaris
- Conditions
- Acne VulgarisToxoplasmosis
- Interventions
- Diagnostic Test: Free testosterone levels and toxoplasma igG
- Registration Number
- NCT05783778
- Lead Sponsor
- Sohag University
- Brief Summary
Acne vulgaris is one if the most common chronic inflammatory skin disorders.Acne is characterized by forming of inflammatory and non inflammatory lesions mainly on the Face,neck,arms, upper trunk and back
- Detailed Description
One of the hidden hormonal imbalance is Toxoplasma infection.Toxoplasmosis is a zoonotic infection the definite host is feline whereas human and other warm blooded animals are intermediate host . Endocrine alterations occuring during toxoplasmosis can be a hidden cause of acne vulgaris
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- Female
- Target Recruitment
- 200
- Female patients with active acne vulgaris
- Patients with history of hormonal treatment Patients received anti toxoplasma therapy Patients with dermatological diseases caused by hormonal disturbances Pregnant and lactating patients
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Toxoplasmosis seropositive female patients with active acne vulgaris Free testosterone levels and toxoplasma igG - Toxoplasmosis seronegative in female patients with active acne vulgaris Free testosterone levels and toxoplasma igG -
- Primary Outcome Measures
Name Time Method Measuring Toxoplasma igG and free testosterone in acne vulgaris patients and controls One month Detect if the toxoplasma latent infection can be associated with disease severity and hormonal disturbances in acne vulgaris female patients
- Secondary Outcome Measures
Name Time Method