Effect of exercise training in inflammatory process control in patients with chronic obstructive pulmonary disease

Not Applicable

Recruiting

• Conditions: Pulmonary Disease, Chronic Obstructive; C08.381.495.389

• Registration Number: RBR-3vt4bs
• Lead Sponsor: Hospital das Clínicas da Faculdade de Medicina da USP

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-11-19
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with chronic obstructive pulmonary disease; aged over 50 years; non smokers, of both genders; clinically stable; who have not participated in regular physical training in the last 6 months

Exclusion Criteria

Patients with other chronic lung disease; or with rheumatoid arthritis; multiple sclerosis; decompensated diabetes; autoimmune hepatitis; chronic cardiovascular disease; malignant tumor; or with acquired immunodeficiency syndrome - AIDS; use of immunosuppressive drugs; presence of musculoskeletal disorders that make it impossible to perform physical exercise; continuous use of oxygen therapy

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expected to find an increase of 2% of anti-inflammatory cells and cytokines, evaluated in peripheral blood by flow cytometry, in chronic obstructive pulmonary disease patients who will perform the exercise training compared to patients who will perform the placebo exercise.

Secondary Outcome Measures

Name	Time	Method
It is expected that the increase in anti-inflammatory response is related to the improvement of clinical symptoms and quality of life, assessed through validated questionnaires, of chronic obstructive pulmonary disease patients who will perform the exercise training.