PrevaLence of Albuminuria in Patients With CARdiovascular Disease and Type 2 Diabetes Mellitus in China: a National Cross-sectional Study
- Conditions
- Type 2 Diabetes MellitusCardiovascular Disease
- Registration Number
- NCT06336239
- Lead Sponsor
- Beijing Anzhen Hospital
- Brief Summary
The association between Cardiovascular Disease (CVD) and Chronic Kidney Disease (CKD) is well established. Traditional risk factors for CVD and CKD are similar, with type 2 diabetes mellitus (T2DM) being the most prevalent risk factor. However, CKD is underdiagnosed and undertreated in patients with CVD. Further understanding of the combination of CKD in CVD patients is important to formulate prevention and treatment strategies for CVD patients and high-risk groups, reduce adverse events in CVD patients, and prevent progression of CKD to End Stage Renal Disease (ESRD).
- Detailed Description
The PLACARD study will include approximately 3,000 patients presenting to the cardiology department with type 2 diabetes and cardiovascular disease. The aim of this study was to assess the prevalence of proteinuria (urinary ACR) in type 2 diabetic patients with different cardiovascular diseases, both inpatient and outpatient in the cardiology departments of secondary and tertiary hospitals in China. Participants will be recruited at 30 clinical centers for a period of six months.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 3000
- Age ≥18 years old;
- Diagnosed T2DM combined with ≥1 CVD (hypertension, coronary heart disease, atrial fibrillation, heart failure);
- During the data collection period, they went to the outpatient clinic of the cardiology department of the research center, or received treatment in the cardiology department;
- Ability to self-sign informed consent (electronic /paper).
-
Pregnant or lactating women;
-
Dialysis patients;
-
Other diseases that lead to elevated albuminuria, such as severe infection, confirmed primary glomerular disease, etc.;
. Malignant tumors being treated (surgery, chemotherapy, radiotherapy or targeted therapy);
-
Cachexia (CSS score ≥ 5 points);
-
Severe liver disease (Child- Pugh grade C) ;
-
Participated in an interventional clinical trial in the past three months.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The prevalence of albuminuria On the day of patients enrollment. To assess the prevalence of albuminuria in patients who are combined with type 2 diabetes mellitus and different cardiovascular diseases in inpatient and outpatient cardiology departments of secondary and tertiary hospitals in China.
- Secondary Outcome Measures
Name Time Method Evaluate the management of patients with type 2 diabetes mellitus and cardiovascular disease across different levels of cardiology departments in hospitals. On the day of patients enrollment. Collect clinical assessment data from patients (including test results and the frequency of these tests over the past year), and assess the management of patient-related risk factors and complications by physicians in hospitals of different levels based on the frequency of testing.
Lthe prevalence of microalbuminuria and macroalbuminuria evels of microalbuminuria and macroalbuminuria On the day of patients enrollment. To evaluate the levels of microalbuminuria and macroalbuminuria of patients with type 2 diabetes mellitus (T2DM) in inpatients and outpatients cardiology departments;
The prevalence of microalbuminuria and macroalbuminuria On the day of patients enrollment. To evaluate the prevalence of microalbuminuria and macroalbuminuria in patients with T2DM complicated with different cardiovascular diseases
To evaluate the related influence factors of albuminuria and the treatment patterns of CKD patients and non-CKD patients in cardiology departments; On the day of patients enrollment. After outpatient patients receive feedback on their renal function tests, assess whether physicians prescribe new relevant medical orders by recording them. Evaluate the treatment patterns for CKD and non-CKD patients in the cardiology department.
Trial Locations
- Locations (27)
Peking University Third Hospital
🇨🇳Beijing, Beijing, China
Beijing Sixth Hospital
🇨🇳Beijing, Beijing, China
Chinese PLA Army Characteristic Medical Center
🇨🇳Chongqing, Chongqing, China
Luoyang Sixth People's Hospita
🇨🇳Luoyang, Henan, China
Haidong City Second People's Hospital
🇨🇳Haidong, Gansu, China
First Hospital of Hebei Medical University
🇨🇳Shijia Zhuang, Hebei, China
Zhangjiagang Sixth People's Hospital
🇨🇳Zhangjiagang, Jiangsu, China
Shenyang Ninth People's Hospital
🇨🇳Shenyang, Liaoning, China
Tai'an First People's Hospital
🇨🇳Tai'an, Shandong, China
Jining First People's Hospital
🇨🇳Jining, Shandong, China
Shenyang Tenth People's Hospital
🇨🇳Shenyang, Liaoning, China
Jing'an District Central Hospital of Shanghai
🇨🇳Shanghai, Shanghai, China
Zhongshan Hospital Fudan University Qingpu Branch
🇨🇳Shanghai, Shanghai, China
Qinyuan County People's Hospital
🇨🇳Changzhi, Shanxi, China
Shanxi Bethune Hospital
🇨🇳Taiyuan, Shanxi, China
The First Affiliated Hospital of Xi'an Jiaotong University
🇨🇳XI Ail, Shanxi, China
The Fifth People's Hospital of Sichuan Province
🇨🇳Chendu, Sichuan, China
Taizhou Central Hospital
🇨🇳Taizhou, Zhejiang, China
West China Hospital of Sichuan University
🇨🇳Chengdu, Sichuan, China
Fangshan District First Hospital
🇨🇳Beijing, Beijing, China
Ruyang County People's Hospita
🇨🇳Luoyang, Henan, China
Yongcheng People's Hospital
🇨🇳Yongcheng, Henan, China
The First Affiliated Hospital of Zhengzhou University
🇨🇳Zhengzhou, Henan, China
Weihai Central Hospital
🇨🇳Weihai, Shandong, China
The First Affiliated Hospital of Xinjiang Medical University
🇨🇳Ürümqi, Xinjiang, China
Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
🇨🇳Shanghai, Shanghai, China
The First Affiliated Hospital of Sun Yat-sen University
🇨🇳Guangzhou, Guangdong, China