Protocols for Prevention of PPH During CS in High Risk Group
- Conditions
- Atonic PPH
- Interventions
- Drug: Syntocinon, papal, misotac
- Registration Number
- NCT05099575
- Lead Sponsor
- Assiut University
- Brief Summary
PPH is one of the most leading causes of maternal mortality,. It means loss of 500 ml blood after vaginal delivery and 1000 ml blood after cesarean delivery. Although it's preventable it represents about 27%of maternal deaths. Atony is the main cause of PPH. 70%of PPH corresponds to uterine atony. Uterotonics like oxytocin, misoprostol, ergometrine, carbetocin and combinations of these drugs can be used but until now there is no agreement on medication that can be the most effective.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 448
Inclusion Criteria
-
- Pregnant full term>37 w 2. Maternal age 19- 40 3.physical state 1&2 4.patient willing to enter the study
Exclusion Criteria
- 1.who refuse to participate in study 2.immunocomprmized and patients who had contraindicated from any of drugs used 3.patients with hypersensitivity to any drug
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Pregnant women who receive oxytocin Syntocinon, papal, misotac - Pregnant women who receive misoprostol Syntocinon, papal, misotac - Pregnant women who receive ergometrine Syntocinon, papal, misotac - Pregnant Women who receive carbetocin Syntocinon, papal, misotac -
- Primary Outcome Measures
Name Time Method Amount of blood loss 1 year Decrease amount of blood loss
- Secondary Outcome Measures
Name Time Method Finding the drug most effective with least adverse effects 1 year