RETRIeVE: ReversE TranscRiptase Inhibitor hiV Practice

Completed

• Conditions: HIV Positive

• Registration Number: NCT01154556
• Lead Sponsor: Holdsworth House Medical Practice

Brief Summary

An observational retrospective study of NNRTI experienced patients who have virologically failed. The study aims to assess resistance profiling and subsequent prescription patterns of patients on NNRTIs

Detailed Description

This is a cross-sectional study involving retrospective review of HIV-1 positive patient records who began treatment with a non-nucleoside reverse transcriptase inhibitor (NNRTI) and subsequently failed. Patients who have virologically failed previous NNRTI treatment, or have resistance to 1 drug in the NNRTI class are examined further. Such patients will have attended the clinic every 3-6 months for routine medical care. The data source for variables collected is the patient's electronic medical records. This database is located at Holdsworth House Medical Practice (HHMP), Sydney.

Study Timeline

• Study Start: 2010-06
• Study First Submitted: 2010-06-30
• Study First Submitted QC: 2010-06-30
• Study First Posted: 2010-07-01
• Primary Completion: 2011-09
• Study Completion: 2013-02
• Status Verified: 2015-09
• Last Update Submitted: 2015-09-17
• Last Update Posted: 2015-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2044

Inclusion Criteria

1. Documented HIV infection
2. Attended Holdsworth House Medical Practice 1999-2009.
3. Chosen ART regime includes an NNRTI

Exclusion Criteria

N/A

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
resistance profiling and subsequent prescription patterns of patients on NNRTIs	1 year

Trial Locations

Locations (1)

Holdsworth House Medical Practice; 🇦🇺 Darlinghurst, New South Wales, Australia