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Clinical Trials/NCT05440760
NCT05440760
Recruiting
Not Applicable

Using Virtual Reality Technology to Improve Patient Experience and Quality of Care During Brachytherapy

University of Arkansas1 site in 1 country20 target enrollmentAugust 8, 2022

Overview

Phase
Not Applicable
Intervention
The Oculus Quest 2 Virtual Reality Headset
Conditions
Endocervical Cancer
Sponsor
University of Arkansas
Enrollment
20
Locations
1
Primary Endpoint
The number of times a technical problem occurs with the VR distraction
Status
Recruiting
Last Updated
2 days ago

Overview

Brief Summary

The primary objective is to demonstrate the feasibility of incorporating VR distraction into the brachytherapy and radiotherapy clinical workflow.

The secondary objective is to determine if VR distraction during brachytherapy treatment for cervical cancer improves subjects' satisfaction, procedural/acute pain, and need for analgesics or anxiolytics.

Detailed Description

This will be a prospective pilot study conducted at UAMS. All subjects will experience VR distraction using a crossover design in which each subject receives four rounds of brachytherapy: two rounds with VR distraction and two rounds without VR distraction. Brachytherapy will be conducted per SoC workflow. Subjects will be placed into four treatment-sequence groups in a 1:1:1:1 allocation ratio via permuted block randomization with randomized block sizes of four or eight. The four treatment-sequence groups will follow the four-session treatment schedules outlined below, in which "V" denotes the sessions when VR distraction is used while "N" denotes the sessions when it is not: * Sequence Group A will be treated according to schedule VVNN. * Sequence Group B will be treated according to schedule VNNV. * Sequence Group C will be treated according to schedule NNVV. * Sequence Group D will be treated according to schedule NVVN.

Registry
clinicaltrials.gov
Start Date
August 8, 2022
End Date
December 1, 2028
Last Updated
2 days ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Female, ≥ 18 years of age
  • Histopathologic diagnosis of gynecologic cancer (endometrial, cervical, vaginal, vulvar) that requires intracavitary brachytherapy with a tandem or interstitial brachytherapy
  • Able to provide written consent

Exclusion Criteria

  • Severe vision or hearing problems that may hinder the ability to see or hear clearly through the VR headset or other condition that may interfere with the placement of the VR headset such as a head, ear or facial wound
  • History of seizure disorder, severe motion sickness, dizziness, or migraine headaches precipitated by visual auras
  • Known history of elevated intraocular pressure
  • Claustrophobia, thalassophobia, cleithrophobia or similar phobias
  • Any other significant medical or psychiatric conditions which, in the opinion of the enrolling investigator, may interfere with consent or compliance of the treatment regimen

Arms & Interventions

Sequence Group A

VR distraction occurring visits 1 and 2 with normal SOC therapy at visits 3 and 4.

Intervention: The Oculus Quest 2 Virtual Reality Headset

Sequence Group B

VR distraction occurring visits 1 and 4 with normal SOC therapy at visits 2 and 3.

Intervention: The Oculus Quest 2 Virtual Reality Headset

Sequence Group C

VR distraction occurring visits 3 and 4 with normal SOC therapy at visits 1 and 2.

Intervention: The Oculus Quest 2 Virtual Reality Headset

Sequence Group D

VR distraction occurring visits 2 and 3 with normal SOC therapy at visits 3 and 4.

Intervention: The Oculus Quest 2 Virtual Reality Headset

Outcomes

Primary Outcomes

The number of times a technical problem occurs with the VR distraction

Time Frame: 3 weeks

The number of eligible subjects who enroll onto the study.

Time Frame: 3 weeks

The number of subjects who withdraw or are withdrawn from the study.

Time Frame: 3 weeks

The number of subjects who successfully complete the study questionnaires for satisfaction, procedural pain, and anxiety.

Time Frame: 3 weeks

Secondary Outcomes

  • Determination of VR distraction during brachytherapy treatment for cervical cancer pain(3 weeks)
  • Determination of VR distraction during brachytherapy treatment for cervical cancer on anxiety.(3 weeks)
  • Opiod dose(3 weeks)
  • Benzodiazepine dose(3 weeks)

Study Sites (1)

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