A clinical trial to study the effects of two drugs,Azilsartan and Losartan in patients with high blood pressure

Not Applicable

Completed

• Conditions: Health Condition 1: I10- Essential (primary) hypertension

• Registration Number: CTRI/2020/08/027209
• Lead Sponsor: PIMS

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-12-12
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 105

Inclusion Criteria

New patients with hypertension i.e not on any antihypertensive therapy.

2. Adult males and females of age 18 years or more.

Exclusion Criteria

1.Sitting clinic diastolic BP (DBP) >114ââ?¬Æ?mm Hg

2.Patients already on anti-hypertensives.

3.Patients with hypersensitivity to AZL or Losartan.

4.Pregnant/ lactating women/ women planning to conceive.

5.Evidence of severe renal disorder.

6.Patients with hepatic insufficiencies.

7.Patients unwilling or unable to comply with the study proceedings.

8.Patients with severe bradycardia, cardiogenic shock, heart block, sick sinus syndrome, decompensated heart failure, bronchial asthma, hypothyroidism, CVA, CAD.

9.Patients with other co morbidities like hyperthyroidism, anxiety disorders.

10.Patients with refractory hypertension.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The end point of the study is attainment of BP 140/90 mmHg for all patients and then maintains it.Timepoint: The SBP will be measured at the end of 24 weeks and compared between the two groups.