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Imaging and urine biomarkers for renal tumor assessment.

Conditions
renal tumor
C64
Malignant neoplasm of kidney, except renal pelvis
Registration Number
DRKS00029264
Lead Sponsor
Department of Diagnostic and Interventional Radiology, University Medical Center Goettingen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
905
Inclusion Criteria

patients age > 18yo with radiologically or urological suspected renal tumor receiving CT imaging; or those undergoing systemic therapy for renal tumors

Exclusion Criteria

patients unable for comprehend the consent for study participation

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1) for non-metastatic RCC: development of a deep learning algorithm combining CT-imaging-data, clinical information, and urine biomarker expression to predict renal tumor histological subtype and malignancy.<br><br>2) for metastatic RCC (mRCC): development of a deep learning algorithm combining CT-imaging-data, clinical information, and urine biomarker expression to predict renal tumor histological subtype, molecular expression patterns and response to systemic therapy.
Secondary Outcome Measures
NameTimeMethod
inter- / intrareader reliability of radiologists; progression-free, cancer-free and overall survival
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