NCT00926926CompletedPhase 1
Effect of Oxybutynin Chloride Topical Gel on Gastric Emptying, Using the Acetaminophen Absorption Test
Watson Pharmaceuticals0 sites23 target enrollmentStarted: June 2009Last updated:
Conditions
Interventions
Drugs
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- Enrollment
- 23
- Primary Endpoint
- The effect of oxybutynin chloride topical gel administration on gastric emptying will be assessed by comparing the single dose relative bioavailability of acetaminophen
Study Overview
Brief Summary
This study explores the effect of oxybutynin topical gel on gastric emptying
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Basic Science
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Adult, healthy, post-menopausal females
Exclusion Criteria
- •Patients for whom OTG or acetaminophen is contraindicated.
- •Abnormality of the GI tract.
- •Taking drugs that affect gastric motility.
Arms & Interventions
Active OTG
Experimental
Intervention: Oxybutynin Chloride Gel (Drug)
Placebo
Placebo Comparator
Intervention: Placebo Gel (Drug)
Outcomes
Primary Outcomes
The effect of oxybutynin chloride topical gel administration on gastric emptying will be assessed by comparing the single dose relative bioavailability of acetaminophen
Time Frame: After 7 days of treatment
Secondary Outcomes
No secondary outcomes reported
Investigators
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