To assess pain reducing efficacy of Ultrasound guided Erector Spinae Block versus Quadratus Lumborum III Block in patients undergoing Unilateral Percutaneous Nephrolithotomy Surgery under General Anesthesia

Not yet recruiting

Conditions: Calculus of kidney with calculus of ureter,

Registration Number: CTRI/2023/06/053543

Lead Sponsor: Dr Pooja Singh

Brief Summary: This is a prospective observational study to be conducted on total of 78 patients of age between 18 to 65 years of either sex belonging to ASA grade I,II and III undergoing elective unilateral percutaneous nephrolithotomy surgery under general anaesthesia in All India Institute of Medical Sciences, Bhopal after undergoing routine investigations and pre anesthetic check up .An informed written consent will be obtained from patient and legally acceptable witness.Patient will be randomly allocated to either group E, receiving Erector spinae plane block :ESPB or group Q receiving quadratus lumbarm block III :QLB III through computer based allocater . In operation theatre all standard ASA monitoring will be attached and baseline vitals will be recorded including blood pressure ,ECG ,SpO2 , temperature. After induction of general anaesthesia and securing airway ,patient will be positioned according to block i .e. lateral position for QLB III and prone position for ESPB . Block will be performed after satisfactory placement of needle under ultrasound guidance and confirming by injecting 1- 2 ml of saline ,once confirmed 20 ml of inj. BUPIVACAINE 0.25% will be injected. Intraoperative hemodynamic monitoring will be done and Inj FENTANYL 1-2 mcg/kg will be given if heart rate or blood pressure or both increases more than 20% of baseline. After the completion of surgery ,complete recovery from nesthesia and achieving adequate level of consciousness patient will be shifted to postoperative recovery room. Hemodynamic parameters will be monitored for 1 hour and patient will be shifted to ward .NRS scores will be assessed at interval of 1,2,6, 12 and 24 hours postoperative at rest and during activity. If NRS score is >= 3 injection paracetamol 1 gram will be given as rescue drug. If pain persists then injection tramadol 50 mg slow i.v. infusion will be given as second analgesia . NRS scores will be furthers according to timeline and total total dose of tramadol is calculated over 24 hours.Post operative complications will also be monitored.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 78

Inclusion Criteria

Study will include patients between 18 to 65years of either sex with ASA physical status 1 to 3 planned for elective percutaneous nephrolithotomy.

Exclusion Criteria

Patientâ€™s refusal to the procedure.
Contraindications to regional technique e.g., allergy to local anesthetic drugs, infection around site of block, any coagulation disorder, sepsis Body mass index > 35kg/m2 Pregnancy Physical or mental disorders that would interfere with evaluation of pain.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine and compare postoperative pain relief using the numeric rating scale (NRS) score between the group E and group Q	At 1 hour, 2 hours, 6 hours, 12 hours and 24 hours postoperatively at rest and during activity

Secondary Outcome Measures

Name	Time	Method
1.To determine & compare the time of the first analgesic.	2.To determine and compare the total perioperative opioid consumption in 24 hours

Trial Locations

Locations (1): AIIMS BHOPAL
🇮🇳
Bhopal, MADHYA PRADESH, India
AIIMS BHOPAL
🇮🇳Bhopal, MADHYA PRADESH, India
Dr Yamini Arora
Principal investigator
9463458927
YAMINIA.jr2022@aiimsbhopal.edu.in