Effect of Nettle in treatment of menopausal hot flash
- Conditions
- Menopause.Menopausal and female climacteric states
- Registration Number
- IRCT20110809007265N11
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 42
Post-menopausal women (defined as: amenorrhea for 12 months or more) who suffer from hot flashes.
Age 45-60 years old
Approval for treatment of hot flashes and consent to participate in the plan.
History of hysterectomy or oophorectomy
Anticancer therapies due to malignancy
History of estrogen-dependent cancers over the past five years
History of allergy to urticaria
History of known psychiatric disorders
Hyperthyroidism or hypothyroidism
Conditions and physical illnesses that are not suitable for this study: Cardiovascular disease (coronary artery disease, cerebrovascular disease and thromboembolic disorders) uncontrolled Hypertension or diabetes, kidney or liver failure
use of anticoagulants
Taking any medication for hot flashes such as HRT and SSRI in the past eight weeks
Endometrial thickness over 12 mm in uterine ultrasonography
Vaginal bleeding with unknown origin in the past 6 months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of FSH, estradiol, LH. Timepoint: Before the study and at week 8. Method of measurement: blood test.;Severity of menopausal symptoms. Timepoint: Before the intervention, week 4 and 7. Method of measurement: Menopausal Rating Scale questionnaire.;Number and severity of hot flashes per day. Timepoint: One week before the study and at weeks 5 and 8. Method of measurement: Patient Daily Report.
- Secondary Outcome Measures
Name Time Method