NCT00463255已完成3 期
Phase IV Interventional Study: Effect of Diet on Brain Function in Elderly Healthy People
University Hospital Muenster1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2006年8月1日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- implicit visual-motor learning of a finger sequence of the hand.
研究概览
简要总结
We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.
详细描述
The age-related degradation of cognitive functions even to the point of neurodegenerative disorders such as alzheimer's disease are a growing public-health concern with potentially devastating effects.
Refering to animal data and empirical studies, a healthy diet rich in unsaturated fatty acids and low in calories should improve cognitive functions such as learning and memory. To test this hypothesis, we study general brain functions in healthy elderly subjects (50-80 years old) during a short term diet.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy subjects
- •50-80 years old
- •moderate to heavy weight
- •must be able to change diet at home
排除标准
- •younger than 50 years
- •BMI < 23
- •already participating in other studys
- •MMSE > 26
- •eating disorders
结局指标
主要结局
implicit visual-motor learning of a finger sequence of the hand.
次要结局
- implicit learning of an artificial language
- several plasma levels related to cognitive functions
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Effect of Mediterranean Diet and Probiotics in Adults With Mild Cognitive ImpairmentMild Cognitive ImpairmentNCT05029765Pablo Pérez Martínez50
已完成
1 期
Low Fat Diet and Multiple SclerosisMultiple SclerosisNCT00852722Oregon Health and Science University61
已完成
2 期
The Effect of a Nutritional Intervention on brain Glucose Metabolism in early Alzheimer*s diseaseearly Alzheimer's disease10029305NL-OMON44286Alzheimercentrum40
招募中
不适用
The Impact of Diet on the Gut-Microbiota-Brain AxisHealthyNCT05931562University College Cork200
尚未招募
Unknown
Research on improving brain function through food intake.Healthy AdultsJPRN-UMIN000052112EAS Inc24