Prognostic Contribution of Abdominal Ultrasound in Necrotizing Enterocolitis in Preterm Infants Less Than 33SA.
试验速览
- 阶段
- 不适用
- 入组人数
- 95
- 试验地点
- 2
- 主要终点
- Comment prognostic evaluation by abdominal ultrasound
研究概览
简要总结
Enterocolitis necrotizing (ECUN) is a common and serious gastrointestinal disease in premature infants.
The diagnosis of ECUN based on clinical and radiological criteria. The abdomen plain film to date is the reference examination to confirm or refute the diagnosis. Indeed, the presence of pathognomonic signs (pneumatosis, aéroportie) on the abdomen of cliché can confirm the diagnosis. The prognostic value of these radiographic findings is currently controversial.
Abdominal ultrasound is a test whose possibilities in diagnostic and prognostic term began to be considered for some years. It also has other advantages, including that of not being a radiating examination. Studies on the prognostic value of abdominal ultrasound are rather few. Moreover, they involve a series of heterogeneous patients in terms of gestational age. Or the pathophysiology of ECUN in children born at term and in children born prematurely is not the same.
The objective is to study prospectively the prognostic contribution of abdominal ultrasound in the ECUN in premature under 33SA.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- — 至 33 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Birth Term strictly less than 33SA
- •Gestational age some (assessed on early ultrasound dating)
- •Congenital malformation of Absence
- •Suggestive clinical symptomatology of ECUN defined by the presence of abdominal bloating, increased residues (> 20% of the volume of enteral feeding) and the presence of blood in stool (macro- or microscopic)
- •Radiologic investigation with a radiograph of abdomen and abdominal ultrasound done for the episode of ECUN
- •Maximum interval between imaging tests 2 hours
- •No parental opposition to the participation of children in the study
排除标准
- •Term higher or equal to 33 weeks
- •Congenital malformation
- •Parental Opposition (or legal representatives) to participate in the study
结局指标
主要结局
Comment prognostic evaluation by abdominal ultrasound
时间窗: 36 months
Assessment in clinical outcome prognosis by abdominal ultrasound
次要结局
未报告次要终点