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Clinical Trials/NCT06972147
NCT06972147RecruitingNot Applicable

Prevalence and Description of FIRE (Food Induced Immediate Response of the Esophagus) in the Pediatric Population With Eosinophilic Esophagitis

University Hospital, Angers2 sites in 1 country40 target enrollmentStarted: July 1, 2025Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Sponsor
Enrollment
40
Locations
2
Primary Endpoint
diagnosis of FIRE syndrome
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

A new clinical entity of eosinophilic esophagitis, Food Induced Immediate Response of the Esophagus or FIRE, has been described since 2020. Diagnostic criteria are not clearly established. Specific questioning is necessary for differential diagnosis, such as the oro-pharyngeal syndrome notably described in pollinics, or a mechanical blockage strictly speaking linked to esophagitis. The aim is to obtain epidemiological data on this entity.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
6 Years to 17 Years (Child)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Patients over 6 and under 18 years of age at the time of inclusion
  • •Follow-up in the allergology unit of Angers University Hospital for eosinophilic esophagitis

Exclusion Criteria

  • •Patients or legal representative with severe communication or language comprehension difficulties
  • •Patients or legal representatives objecting to study participation

Outcomes

Primary Outcomes

diagnosis of FIRE syndrome

Time Frame: day 1

symptoms such as pain, pressure, choking or narrowing, in the oesophagus or retrosternum, within 10 minutes of ingestion, lasting a maximum of 120 minutes, when a specific food is ingested

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
University Hospital, Angers
Sponsor Class
Other Gov
Responsible Party
Sponsor

Study Sites (2)

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