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Clinical Trials/NCT02310529
NCT02310529
Completed
Not Applicable

Randomized Control Trial of an Interpersonal Psychotherapy for Maternal Depression

Pakistan Institute of Living and Learning4 sites in 1 country50 target enrollmentMarch 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Maternal Depression
Sponsor
Pakistan Institute of Living and Learning
Enrollment
50
Locations
4
Primary Endpoint
Edinberg Postnatal Depression Scale (EPDS) To test the feasibility and acceptability of interpersonal psychotherapy in women suffering from postnatal depression.
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Depression related to pregnancy frequently presents postpartum depression, which has deteriorating and lasting negative effects, not only on infant and child well being but also on mother's and father's mental health (Nancy K et al 2009). It is therefore important to introduce interventions aiming to improve mental health of mothers that could minimize the risk of diseases, and have positive effect child's on physical and psychological developmental wellbeing.

Therefore, this project has been designed to assess the effectiveness of Interpersonal Psychotherapy for Postnatal Depression in Pakistan.

Detailed Description

Prevalence of depression in the postnatal period is 10% to 17 % in western world ( O 'Hara and Swain 1996; Josseffson et al 2001; Yoshida et al 2001) and 23% to 36% in the developing world (Rahman et al 2003; Patel et al 2002; Husain et al 2006). In developed countries, studies indicate that maternal depression is associated with long-term emotional, cognitive and behavioral problem in children. There is evidence of link between maternal psychopathology to physical health of child. Research evidence also indicates that long-term negative impact of postnatal depression is on the mother's mental health, on infant's development and on the marital relationship (Reay, Fisher, Robertson, Adams and Owen 2005). because of high prevalence of maternal depression in low income countries like Pakistan, the present study is designed to test the effectiveness of Interpersonal Psychotherapy for women with maternal depression. The participants will be recruited from Civil hospital Karachi and also from three different communities. total 50 participants will be recruited and randomized to 2 groups: either intervention or TAU group. Assessment will be done on baseline, after completion of intervention and 3 months after completion of intervention. Assessment will include Edinburg Postnatal depression scale, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7 and Rosenberg Self Esteem scale. Participants in intervention group will receive 12 sessions of Interpersonal Psychotherapy (IPT)

Registry
clinicaltrials.gov
Start Date
March 2014
End Date
January 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Mothers age 18 years and above older with child below 3 years of age
  • Meet the criteria for mild to moderate depressive symptoms on (EPDS (cut off score above 10) and
  • Were resident of trial catchment area were included in the study.

Exclusion Criteria

  • Mothers who were suffering from severe depression, with diagnosed learning or physical disability or
  • Any major psychiatric illness other than maternal depression, with Alcohol and substance dependent or
  • Actively suicidal were excluded from the study.

Outcomes

Primary Outcomes

Edinberg Postnatal Depression Scale (EPDS) To test the feasibility and acceptability of interpersonal psychotherapy in women suffering from postnatal depression.

Time Frame: 3 months

EPDS will be used to assess depression

Secondary Outcomes

  • Generalized Anxiety Disorder-7 (GAD-7)(3 and 6 Months)
  • Rosenberg Self Esteem Scale (RSES)(3 and 6 Months)
  • Patient Health Questionnaire-9 (PHQ-9)(3 and 6 Months)

Study Sites (4)

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