Electroencephalographic Correlates of Glove-stretch Therapy Post-stroke
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Rate of activation of Event Related Desynchronization
研究概览
简要总结
The purpose of this study is to measure how cortical signals improve in stroke participants after passive hand stretching therapy from a robotic glove.
详细描述
After experiencing a stroke event, many individuals are left with life-long motor impairments in their upper extremity. However, motor recovery for stroke survivors is not fully understood. One of the challenges to understand the mechanisms behind recovery is the capability of the brain to reorganize and re-activate areas affected by the stroke. Brain computer interface (BCI) has shown promise in previous studies to improve motor capabilities of individuals with damaged nervous systems by reactivating damaged motor pathways.
In order to understand how BCI can be incorporated into upper extremity rehabilitation, investigators must first lay the groundwork of measuring neural activity and its relation to muscle activity in individuals who have experienced a stroke. While instructing participants to open and close their hand, investigators will measure (1) neural activity, called sensorimotor rhythms (SMRs), using a electrophysiological (EEG) cap, and (2) muscle activity using wireless electromyography (EMGs). What the investigators are specifically looking for is an event in the neural activity in between movement initiation and termination called event related desynchronization (ERD). The investigators of this study hypothesize that there is greater activation of ERDs in stroke's subjects SMR activity after completing finger extension and flexion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ischemic or hemorrhagic stroke (6 months post stroke)
- •Hemiparesis
- •Some degree of hand and finger movement capability
- •a moderate impairment (Fugl-Meyer score between 15-50)
排除标准
- •Individuals under the age of 18
- •Bilateral paresis
- •Hand pain and/or extreme articular contractures on the finger joints (Modified Ashworth Scale of 4)
- •Botox injection to the affected upper extremity within the previous 4 months
- •Aphasia, cognitive impairment, or affective dysfunction that would influence the ability to perform the experiment
结局指标
主要结局
Rate of activation of Event Related Desynchronization
时间窗: 1 hour
Sensorimotor neural activity
次要结局
未报告次要终点
研究者
James Patton
Director, Robotics Laboratory, Arms and Hands Lab
Shirley Ryan AbilityLab
