The effect of long-term Momordica Charantia supplementation on blood glucose levels

• Conditions: blood glucose; pre-diabetes; 10018424

• Registration Number: NL-OMON51413
• Lead Sponsor: Wageningen Food and Biobased Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

• Age 40-75yrs
• BMI >25 kg/m2
• Having a fasting glucose >= 5.6 mmol/L

Exclusion Criteria

• Use of medication/supplements that may influence the study results, such as
metformin, gliclazide, glimepiride, tolbutamide, insulin, sitagliptin (DPP4
inhibitor), liraglutide (GLP-1 agonist), acarbose, repaglinide, pioglitazone,
corticosteroids (systemically) , SGLT-2 inhibitors, (judged by our research
physician)
• Having a fasting glucose >11.0 mmol/L
• History of gastro-intestinal surgery or having (serious) gastro-intestinal
complaints
• History of liver dysfunction (cirrhosis, hepatitis) or liver surgery
• Kidney dysfunction (self-reported)
• Reported slimming, medically prescribed or other extreme diets
• Reported weight loss or weight gain of > 5 kg in the month prior to pre-study
screening
• Not willing to give up blood donation during the study
• Current smokers
• Alcohol intake >=14 glasses (women) or >21 glasses (men) of alcoholic
beverages per week, on average
• Not pregnant or lactating
• Abuse of illicit drugs (soft- and hard drugs)
• Food allergies for products that we use in the study
• Participation in another clinical trial at the same time
• Being an employee of the Food, Health & Consumer Research group of Wageningen
Food & Biobased Research or dept. human nutrition and health of Wageningen
University.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is fasting levels of plasma glucose. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-</p><br>