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Heart and Renal Failure in Hip Fracture Surgery

Completed
Conditions
Heart Injuries
Renal Insufficiency
Hypotension
Hip Fractures
Registration Number
NCT03532919
Lead Sponsor
Sahlgrenska University Hospital, Sweden
Brief Summary

Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as well as renal failure noted by Changes in Serum Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP

Detailed Description

Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as awell as renal failure noted by Changes in S Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as a step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
105
Inclusion Criteria
  • Hip fracture patient to be operated upon Classified as being ASA 3 or more
Exclusion Criteria
  • Not forfilling inclusion Criterias

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Mortality90 days

post surgery

Secondary Outcome Measures
NameTimeMethod
Serum concentrations of Troponin, NTproBNP, Creatinin and Cystatin C90 days

Relations between values and mortality at 30 and 90 days

Trial Locations

Locations (1)

Sahlgrenska University Hospital

🇸🇪

Molndal, Vastra Gotaland, Sweden

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