Methadone in chronic non-cancer pain: rotation from other opioids and choice of dose
- Conditions
- Chronic non-cancer pain
- Registration Number
- EUCTR2004-005035-26-SE
- Lead Sponsor
- Anesthesiology Clinic,Akademiska Sjukhuset, Uppsala
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Chronic non cancer pain which has responded poorly to other opioids than methadone
Men and women older than 18
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Impossibility to take oral medication
Renal or liver functional impairment
Difficulties in communication
Cognitive impairment
Use of other medicinal products which will not be combined with methadone (se protocol)
Pregnancy(prevention according to agreement with the patient)
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: To find out if you can predict the dose methadone needed for good pain relief based on the dose of the previoud opioid and genetic metabolic pattern;Secondary Objective: To evaluate the benefits of methadone treatment in long trem treatment of chronic non malignant pain;Primary end point(s): Pharmacokinetic study
- Secondary Outcome Measures
Name Time Method