Postural orthostatic tachycardia syndrome (POTS) in Long COVID syndrome: A detailed profiling study

The University of Adelaide0 个研究点目标入组 218 人开始时间: 2021年4月21日最近更新: 2023年10月30日

适应症

试验速览

暂无简介。

•Cohort 1 (LCS): Adults aged 18 years old or greater (male or female); Able to provide written informed consent; previous SARS-CoV-2 infection (As some Australians contracted SARS-CoV-2 in countries that did not undertake testing in the early stages of the pandemic, some participants will not have a diagnosis by PCR. Inclusion with physician confirmed Long Covid is consistent with worldwide research practices for Long Covid studies); continuing chronic symptoms persisting for greater than 3 months post-acute COVID-19 infection and not attributable to an alternative disease state.
•Cohort 2 (POTS): Adults aged 18 years old and older (male or female); POTS diagnosis; Able to provide written informed consent; Diagnostic criteria for POTS met as per the following: 1. sustained heart rate elevation of 30 beats/min or greater within 10 minutes. 2. No other secondary cause of these symptoms. 3. Absence of orthostatic hypotension 4. Symptomatology present for greater than 3 months
•Cohort 3 (Healthy Control): Otherwise, healthy adults aged 18 years old or greater (male or female); Able to provide written informed consent; absence of POTS diagnosis or previous SARS-CoV-2 infection.

•Non-consent for participation in study; pregnancy or lactation; other known causes of autonomic dysfunction; co-morbidities such as Type 1 Diabetes, Parkinson’s disease, multiple sclerosis, alcoholism, drug addiction, malignant neoplasm, recent cerebrovascular accident or transient ischaemic attack, acquired brain injury; significant surgery within the last 3 months; unavailability for completion of all assessments as per the study protocol; non-English speaker; terminally ill with life expectancy <12 months.

发起方