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Clinical Trials/NCT03724110
NCT03724110
Completed
Not Applicable

Telestroke for Comprehensive Transient Ischemic Attack Care in Acute Stroke Ready Hospitals

University of Minnesota5 sites in 1 country300 target enrollmentOctober 2, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Transient Ischemic Attack
Sponsor
University of Minnesota
Enrollment
300
Locations
5
Primary Endpoint
Composite score of TIA treatment (%)
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

TELECAST-TIA is a prospective single-center study evaluating guideline-based transient ischemic attack (TIA) treatment at an Acute Stroke Ready Hospital (ASRH) pre- and post-initiation of a specialist telestroke inpatient rounding service. TELECAST-TIA will study the following clinical endpoints: diagnostic stroke evaluation, secondary stroke prevention, health screening and evaluation, stroke education, inpatient complications, and stroke recurrence rates. Additional relevant non-clinical data will include patient and provider satisfaction scores, transfer patterns, and a cost analysis.

Detailed Description

Telestroke is a validated intervention that improves the triage and emergent treatment of acute stroke, specifically related to the use of intravenous thrombolysis. Effective urgent stroke evaluation and secondary stroke prevention is also essential to decrease the risk of recurrent stroke, however, there have been no studies to date examining the use of telestroke to improve delivery of non-emergent inpatient stroke care per American Heart Association (AHA) guidelines. Currently, access to stroke specialist expertise is limited resulting in significant disparities in stroke care. Previous publications have identified that patients in rural areas may receive sub-optimal stroke care that does not follow accepted guideline recommendations. Telestroke is a cost-effective mechanism to deliver specialist stroke care to hospitals that do not have in-person stroke consultation available. The aim of TELECAST-TIA is to determine whether specialist telestroke inpatient rounding improves guideline-based TIA treatment when compared to non-specialist transient ischemic attack treatment. The primary outcome of TELECAST-TIA is a composite score of 3 categories: diagnostic stroke evaluation, secondary stroke prevention, and stroke education. Individual components of the primary outcome were principally derived from AHA stroke guidelines. Additional outcome measures include individual analyses of the components of the primary outcome as well as the complication rate, stroke recurrence rate, transfer rate, patient and provider satisfaction levels, and a cost-analysis. All outcomes will be assessed at 1 year post-implementation, with data accruement starting after a 3-month lead in phase.

Registry
clinicaltrials.gov
Start Date
October 2, 2018
End Date
July 2, 2022
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age 18 and above
  • Patients with the primary diagnosis of transient ischemic attack evaluated at the Fairview Ridges Hospital emergency room
  • Clinical diagnosis of transient ischemic attack by the treating stroke neurology service

Exclusion Criteria

  • Patients less than 18 years old
  • Patients who leave the hospital against medical advice
  • Patients who are felt to have an alternative diagnosis

Outcomes

Primary Outcomes

Composite score of TIA treatment (%)

Time Frame: 1 year after implementation of the inpatient telestroke service

A 19-item global assessment of fundamental TIA treatment primarily informed by AHA guidelines/GWTG criteria, represented in 3 categories: * Diagnostic evaluation (10 items): neurologist evaluation, LDL, HgA1c, head CT, brain MRI, intracranial vascular imaging, cervical vascular imaging, EKG, telemetry, and outpatient prolonged cardiac monitoring. * Secondary prevention (6 items): antiplatelet, anticoagulation, statin, antihypertensives, diabetes management, and carotid revascularization. * Stroke education (3 items): tobacco cessation counseling, exercise/lifestyle counseling, and signs of stroke. An item is not scored when not indicated clinically (for example tobacco cessation in a non-smoker), therefore the composite scores will be reported and analyzed as percentages.

Secondary Outcomes

  • Diagnostic TIA Evaluation(1 year after implementation of the inpatient telestroke service)
  • Composite Stroke Recurrence(Measured at 3 months and at 1 year after discharge)
  • Secondary Stroke Prevention(1 year after implementation of the inpatient telestroke service)
  • Stroke Education(1 year after implementation of the inpatient telestroke service)

Study Sites (5)

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