Treatment of Depression After Coronary Bypass Surgery
- Conditions
- Interventions
- Registration Number
- NCT00042198
- Lead Sponsor
- Washington University School of Medicine
- Brief Summary
This randomized controlled trial will test the efficacy of (1) cognitive behavior therapy and (2) supportive stress management as treatments for depression in people who have recently undergone coronary artery bypass graft surgery.
- Detailed Description
Depression is a very common problem for people who have had CABG surgery, and recent studies have shown that it may increase the risk of additional medical problems and death during the first few years after surgery. Cognitive behavior therapy (CBT) has been shown to be efficacious for depression in otherwise healthy individuals, and supportive stress manage...
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 123
- Coronary Artery Bypass Graft (CABG) surgery (alone or combined with valvular or carotid surgery) within past 12 months
- Meets DSM-IV criteria for major or minor depressive episode
- Severe cognitive impairment
- Severe psychiatric comorbidity (e.g., alcoholism or schizophrenia)
- Severely debilitating or life-threatening illness other than coronary disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 Cognitive behavior therapy Cognitive Behavior Therapy. The treatment modality was individual, face-to-face therapy with an experienced cognitive therapist. Treatment consisted of up to 12 weekly, hour-long sessions. 2 Supportive Stress Management Supportive Stress Management. The treatment modality was individual, face-to-face therapy with an experienced psychotherapist. Treatment consisted of up to 12 weekly, hour-long sessions.
- Primary Outcome Measures
Name Time Method Hamilton Rating Scale for Depression (HAM-D-17) 12 weeks post-randomization The HAM-D-17 is an observer-rated measure of the severity of depression.
- Secondary Outcome Measures
Name Time Method Beck Depression Inventory 12 weeks post-randomization The BDI is a self-report measure of the severity of depression.
Beck Anxiety Inventory 12 weeks post-randomization The BAI is a self-report measure of the severity of anxiety symptoms.
Beck Hopelessness Scale 12 weeks post-randomization The BHS is a self-report measure of hopelessness.
Perceived Stress Scale 12 weeks post-randomization The PSS is a self-report measure of perceived stress
SF-36 12 weeks post-randomization The Medical Outcomes Study SF-36 is a measure of health-related quality of life. The Physical and Mental factor scores will be reported.
Trial Locations
- Locations (1)
Washington University School of Medicine
🇺🇸St. Louis, Missouri, United States