Pilot Functional Imaging Study to Evaluate Mechanisms Underlying Chronic Pain in Breast Cancer Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pain
- Sponsor
- Lynn Henry
- Enrollment
- 39
- Locations
- 1
- Primary Endpoint
- Determination of differences in pain sensitivity and functional MRI in different groups of patients.
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to better understand why some women with breast cancer develop chronic pain.
Detailed Description
Women with breast cancer who either have chronic pain or who do not have chronic pain will be asked to enroll. Those who participate will have pictures taken of their brain using MRI when they are lying still and also when pressure is being applied to their thumbnails. These pictures will be compared to patients without breast cancer who do not have pain and to those who have other types of pain, such as fibromyalgia. By taking and analyzing these pictures the investigators hope to understand more about why breast cancer survivors develop pain after their diagnosis and treatment. In the future the investigators hope to better treat the pain or possibly even prevent the pain from occurring in the first place.
Investigators
Lynn Henry
Principal Investigator
University of Michigan Rogel Cancer Center
Eligibility Criteria
Inclusion Criteria
- •Breast Cancer Survivor with and without chronic pain
- •Able to undergo MRI
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Determination of differences in pain sensitivity and functional MRI in different groups of patients.
Time Frame: 6 months
The primary objective of this pilot trial is to determine if there may be differences in mechanical pain sensitivity and functional MRI brain activation patterns in breast cancer survivors with chronic pain as compared to breast cancer patients without chronic pain, to patients with fibromyalgia, or to healthy controls.