Characteristics of Pneumothorax Associated With Transthoracic Percutaneous Lung Biopsy in Standard of Care

• Conditions: Pneumothorax Iatrogenic Postprocedural

• Registration Number: NCT05259293
• Lead Sponsor: Centre Hospitalier Universitaire de Besancon

Brief Summary

The number of lung biopsies has increased steadily in recent years. Pneumothorax is the most common complication of a lung biopsy and can occur during the procedure, immediately after the procedure or within a few hours (delayed pneumothorax). The incidence of pneumothorax in the literature is very different from one study to another: it has been reported to be from 9 to 54% in patients undergoing percutaneous transthoracic needle biopsy. This difference of incidence could be explained by the absence of consensus for the definition of an iatrogenic pneumothorax.

The characteristics of pneumothorax and the management of patients with iatrogenic pneumothorax will be evaluated in different centres in a retrospective manner. This study will contribute to refining the criteria for defining pneumothorax occurring during lung biopsy and will provide a better understanding of the condition and its management.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-12-07
• Study Start: 2021-12-09
• Status Verified: 2022-02
• Study First Submitted QC: 2022-02-18
• Last Update Submitted: 2022-02-18
• Study First Posted: 2022-02-28
• Last Update Posted: 2022-02-28
• Primary Completion: 2022-03
• Study Completion: 2022-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Patients aged 18 years old and more at the time of the biopsy procedure in year 2020
• Having had a pneumothorax following their transthoracic percutaneous lung biopsy in year 2020

Exclusion Criteria

• Objection to the use of the data (French sites only)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Annual incidence rate of pneumothorax related to transthoracic lung biopsy on total number of lung biopsies	3 months

Secondary Outcome Measures

Name	Time	Method
Annual incidence rate of hospitalisation in patients with pneumothorax related to lung biopsies	3 months
Annual incidence rate of drainage in patients with pneumothorax related to lung biopsies	3 months

Trial Locations

Locations (6)

Oxford University Hospitals; 🇬🇧 Oxford, United Kingdom

CHU de Besançon; 🇫🇷 Besançon, France

Institut Bergonié; 🇫🇷 Bordeaux, France

CHU de Tours; 🇫🇷 Tours, France

Institut Gustave Roussy; 🇫🇷 Villejuif, France

Saint James Hospital; 🇮🇪 Dublin, Ireland