Exercise related risks during the Nijmegen 4-Day Marches: the influence of hypertensio

Completed

Conditions: Inspannings gerelateerde gezondheidsrisico's (o.a. vocht- en electrolytenbalans, thermoregulatie)
Dehydration
fluid disturbances during exercise

Registration Number: NL-OMON34564

Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 99

Inclusion Criteria

- older than 18 years
- Group 1: participant of 4-Day marches / healthy subjects, normotensive
- Group 2: participant of 4-Day marches / hypertesion in combination with the use of diuretics

Exclusion Criteria

obstructive disease of the gastro-intestinal tract, including diverticulitis and inflammatory bowel disease
- previous gastrointestinal surgery, except cholecystectomy and appendectomy
- MRI during the period that the CorTemp sensor is within the body (e.g. 1 day preceding the 4-Day Marches, during the 4-Day Marches and 2 days after the the 4-Day Marches)
- subject having a cardiac pacemaker or other implanted electromedical device;Additional exclusion criteria for group 1:
- the use of medicaments that interfere with the fluid balance
- the use of medicaments that interfere with the electrolyte balance

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Fluid intake and urine output<br /><br>2) Blood determinations (lipid profile, electrolytes, hematocrit, hemoglobine,<br /><br>creatine kinase, troponin)<br /><br>3) Core body temperature, skin temperature and heart rate<br /><br>4) Energy expenditure<br /><br>5) Personal characteristics (questionnaire)<br /><br>6) Ambient conditions (WBGT)</p><br>

Secondary Outcome Measures