Comparison between the effectiveness of Crocus sativus and Crocin in the treatment of patients with major postpartum depression under common medical care.

Phase 3

Recruiting

• Conditions: major postpartum depression.; Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified Puerperal psychosis NO

• Registration Number: IRCT20130826014477N5
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 September 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 45

Inclusion Criteria

Nursing mothers after their delivery up to the passage of six months
Nursing mothers in the 18-50 age range
Delivery of full-term, healthy, singleton baby
Acceptance of completion of the informed consent form after providing the necessary information on the investigation
Obtaining of an exact diagnosis of the major depressive disorder using Edinburgh questionnaire by a psychiatrist during a clinical examination

Exclusion Criteria

Patients with a history of chronic, systemic diseases
Patients with a history of medical disorders such as preeclampsia and diabetes
Patients allergic to saffron
Smoking cigarettes, drinking alcohol and taking drugs
Patients with a history hepatic and renal disorders

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in mean score of BDI-II. Timepoint: Every two weeks for12 weeks. Method of measurement: BDI_II Questionnaire.