跳至主要内容
临床试验/NCT04058015
NCT04058015已完成不适用

Admission Hyperglycemia in Patients With Moderate to Severe Thoracoabdominal Injuries is Associated With Higher Mortality Rate Than Non-Diabetic Normoglycemic Patients

Chang Gung Memorial Hospital1 个研究点 分布在 1 个国家目标入组 802 人开始时间: 2019年6月3日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
802
试验地点
1
主要终点
in-hospital mortality

研究概览

简要总结

This study aimed to measure the effects of SIH and DH on the mortality outcomes of the adult patients with moderate to severe thoracoabdominal injury

详细描述

Because the pathophysiologic response of the patients with a thoracoabdominal injury is different from those who had a traumatic brain injury, this study aimed to measure the effects of hyperglycemia induced by stress or by diabetes on the outcomes of patients with thoracoabdominal injuries in comparison with those who had non-diabetic normoglycemia (NDN). The primary study hypothesis stated that, following thoracoabdominal injuries, the patients with SIH had a worse outcome than patients with DH. The primary outcome was mortality rate of these patients.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients with moderate to severe thoracoabdominal injuries

排除标准

  • patients with a thoracic and abdominal abbreviated injury scale (AIS) < 3
  • patients who had polytrauma which was defined as there was additional AIS scores ≥ 3 points in other regions of the body
  • patients less than 20 years old
  • patients who had sustained a burn injury

结局指标

主要结局

in-hospital mortality

时间窗: up to 6 months

The primary outcome of the study was in-hospital mortality.

次要结局

未报告次要终点

研究者

发起方
Chang Gung Memorial Hospital
申办方类型
Other
责任方
Sponsor

研究点 (1)

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