Comparison of Serum Calcium Level Between Preoperative Vitamin D and Non-vitamin D Regimen of Total Parathyroidectomy in End-stage Renal Failure Patients in Rajavithi Hospital

Not Applicable

Completed

• Conditions: End Stage Renal Disease
• Interventions: Drug: Alfacalcidol 0.5 MCG Oral Capsule; Drug: Calcitriol

• Registration Number: NCT04967469
• Lead Sponsor: Rajavithi Hospital

Brief Summary

This Research is compare about IV Calcium between end-stage renal failure patients who take vitamin D and non-vitamin D preoperative parathyroidectomy

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-01
• Study First Submitted: 2021-07-08
• Study First Submitted QC: 2021-07-08
• Study First Posted: 2021-07-19
• Status Verified: 2021-08
• Primary Completion: 2023-12-30
• Study Completion: 2023-12-30
• Last Update Submitted: 2024-01-24
• Last Update Posted: 2024-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• New End-stage renal failure patients and have iPTH>800 pg/dl at least 6 months
• Patients who no response hyperphosphatemia with high dose vitamin D

Exclusion Criteria

• Allergy vitamin D
• Pregnancy
• Patients who parathyroidectomy have less than 4 gland

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
take alphacalcidol	Alfacalcidol 0.5 MCG Oral Capsule	End-stage renal failure patients who is Hyperparathyroid with ESRD take 1-hydroxycholecalciferol (alfacalcidol)
take calcitriol	Calcitriol	End-stage renal failure patients who is Hyperparathyroid with ESRD take calcitriol

Primary Outcome Measures

Name	Time	Method
Comparison of serum calcium level between patients who take Vitamin D and non-Vitamin D	4 year	Comparison of serum calcium level between patients who take Vitamin D and non-Vitamin D

Trial Locations

Locations (1)

Rajavithi Hospital; 🇹🇭 Bangkok, Thailand