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Clinical Trials/NCT05090475
NCT05090475CompletedNot Applicable

Evaluating Hospital Educator-led Academic Detailing on Improving Antibiotic Prescribing in Primary Healthcare: a Feasibility Study

General Hospital Koprivnica1 site in 1 country16 target enrollmentStarted: April 1, 2020Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
16
Locations
1
Primary Endpoint
Proportion of antimicrobials expressed as DDD per day for ATC group J01 associated with acute respiratory tract infections

Study Overview

Brief Summary

World increase in mortality from consequences of antimicrobial resistance (AMR) represents a significant public health problem. Irrational prescribing of antimicrobial drugs (AMD) in general population is one of the main causes of development AMR. This is also contributed by fact that up to 90% of total antimicrobial consumption in Europe is related to the general population. Problem of AMR has been recognized by World Health Organization and Council of European Union, which support the establishment of the antimicrobial stewardship team (A-team). A-team provides co-ordinated interventions that promote rational use of AMD. To date, no study has been carried out in which A-team from hospital environment goes to primary health care for the purpose of rationalization prescribing of AMD by primary health care practitioners. Project for implementation of hospital A-team in primary health care in Koprivnica-Križevci County was initiated using academic detailing method aimed at rationalization of the consumption of AMD.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Parallel
Primary Purpose
Health Services Research
Masking
None

Eligibility Criteria

Ages
25 Years to 75 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •All primary care physicians in Koprivnica Križevci County that agree to participate in the study

Exclusion Criteria

  • •Primary care physicians outside Koprivnica Križevci County

Arms & Interventions

Experimental group in Koprivnica Križevci County

Experimental

Hospital A-team provided academic detailing intervention to primary care physicians in Koprivnica Križevci county who agree to participate

Intervention: Academic detailing intervention (Behavioral)

Control group in Koprivnica Križevci county

No Intervention

Primary care physicians in Koprivnica Križevci county who did not agree to participate in academic detailing intervention

Control group in Bjelovar Bilogora county

No Intervention

Primary care physicians in Bjelovar Bilogora county without the academic detailing intervention

Outcomes

Primary Outcomes

Proportion of antimicrobials expressed as DDD per day for ATC group J01 associated with acute respiratory tract infections

Time Frame: 1 year

Rationalization of consumption of antimicrobials for acute respiratory tract infections (for associated ICD diagnoses J01, J02, J03, J06, J20)

Secondary Outcomes

  • Change in Clostridiodes dificile infection for patients on antimicrobial therapy(1 year)

Investigators

Sponsor
General Hospital Koprivnica
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Darija Kuruc Poje

Head of hospital pharmacy, Clinical pharmacist

General Hospital Koprivnica

Study Sites (1)

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