跳至主要内容
临床试验/CTRI/2024/05/067230
CTRI/2024/05/067230已完成不适用

A cross sectional study for estimation of adherence to the institutional antibiotic policy in level III neonatal intensive care unit, Pune, India

Bharati Vidyapeeth medical college and Hospit1 个研究点 分布在 1 个国家目标入组 385 人开始时间: 2024年5月30日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
385
试验地点
1
主要终点
To determine percentage of neonates receiving antibiotic treatment who comply with the Institution’s antibiotic policy.

研究概览

简要总结

Antimicrobials are the most often used classes of medicines in the Neonatal Intensive Care Unit (NICU) with more than 80% of all NICU patients get antibiotics during their hospital stay.WHO identified antibiotic resistance as a persistent danger to public health - made significant changes to the essential medications list, categorizing antibiotics into three categories- aware (access, watch, and reserve) to ensure their availability and proper use.Infection is very common and so is the use of AMAs. Antimicrobial Resistance (AMR)has developed as a result of the complexity and difficulty of treating neonatal sepsis, which has triggered increase use of antibiotics, particularly broader spectrum antibiotics resulted in rise in Antimicrobial Resistance. These difficulties are persistent and more pervasive, according to a more recent systematic review from 2019 on AMR in newborn sepsis in South Asia .It is of paramount importance to use the available AMAs with utmost care. As a result, it will be worthwhile to perform a present study to capture the details of the use of AMAs and to verify its rationality in this institute’s Medical NICU.

研究设计

研究类型
Observational

入排标准

年龄范围
1.00 Day(s) 至 28.00 Day(s)(—)
性别
All

入选标准

  • The neonates will eligible to be enrolled in the study if admitted in NICU who will be given one or more antibiotic.

排除标准

  • The neonates will be excluded from the study if on treatment other than antibiotics or who will get discharge or decease within 24 hours from admission.

结局指标

主要结局

To determine percentage of neonates receiving antibiotic treatment who comply with the Institution’s antibiotic policy.

时间窗: 1 Year

次要结局

  • 1.To ascertain the outcome of neonates treated with antibiotics.(2.To assess proportion of neonates adhering to institutional antibiotic guidelines for Escalation / De-escalation / change of antibiotics)

研究者

发起方
Bharati Vidyapeeth medical college and Hospit
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Shuktika Mishra

Bharati Vidyapeeth medical college and Hospital,Pune

研究点 (1)

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