Role of Adjuvant Yoga Therapy in Managing Withdrawal Symptoms of Patients with Opioid Use Disorder

Not Applicable

• Conditions: Health Condition 1: F112- Opioid dependence

• Registration Number: CTRI/2023/04/051302
• Lead Sponsor: Dr. Suddala Goutham

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 May 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Diagnosis of Opioid use disorder.

Subjects with mild to moderate severity of withdrawal symptoms (Clinical Opiate Withdrawal Scale: COWS score below 24).

Subjects who got admitted into CAM, NIMHANS and started on treatment.

Exclusion Criteria

COWS score more than 25.

Patients not willing to give informed consent.

History of current medical illness that may significantly affect brain functions.

Patients with intractable pain due to other diseases and those on prescribed opioids for the pain of other medical conditions.

Impaired general intellectual functioning (Mini-Mental Status Exam, MMSE below 24).

Past history of head injury or concomitant severe medical conditions.

With co-morbid (alcohol/benzodiazepine/cannabis or multiple) substance dependence except nicotine.

Subjects who had received specific yoga practices for OUD in the past.

Pregnant or post-partum subjects.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Heart Rate Variability (HRV). <br/ ><br>Symptoms severity assessed by Clinical Opiate Withdrawal Scale (COWS). <br/ ><br>Timepoint: Pre(0 days) and post(after 2 weeks) <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
Seeing the immediate effect of 10 minute pranyama technique on HRV in patients with Opioid use disorder who are currently experiencing acute withdrawal symptomsTimepoint: It will be a continuous HRV recording. To see immediate effect. One time point.;Sleep quality. <br/ ><br>Perceived stress. <br/ ><br>Hamilton anxiety rating scale (HAM-A). <br/ ><br>Brief Pain Inventory (BPI) and Algometer for pain threshold. <br/ ><br>Timepoint: Pre(0 days) and post(after 2 weeks)