Study of Imaginomics Predicting Early Surgical Rates in Crohn's Disease

Recruiting

• Conditions: Prognostic Model; Crohn Disease; Radiomics
• Interventions: Other: CTE examination

• Registration Number: NCT05174208
• Lead Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University

Brief Summary

Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic intestinal recurrent inflammatory disease involving the entire digestive tract. Most CD patients require surgery for complications, including stenosis, perforation, and severe intestinal bleeding. Predicting early-onset surgery risk is of great importance to assist launching of therapeutic strategies. We aim to establish a digital prognostic model and nomogram using radiomics, which will help clinical practice.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-09-24
• Study First Submitted QC: 2021-12-29
• Study First Posted: 2021-12-30
• Study Start: 2022-01-01
• Status Verified: 2023-10
• Last Update Submitted: 2023-12-03
• Last Update Posted: 2023-12-05
• Primary Completion: 2024-09-20
• Study Completion: 2024-12-20

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

patients with a confirmed diagnosis of CD; a follow-up more than 1 year; without previous CD-associated intestinal surgeries; complete data of CTE.

Exclusion Criteria

patients without a confirmed diagnosis of CD; with incomplete data and a follow-up less than 1 year; patients have previous intestinal surgeries; patients who have never undergone CTE examination.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
CD	CTE examination	-

Primary Outcome Measures

Name	Time	Method
percentages of surgery at one-year after diagnosis	2017-2021	percentages of surgery at one-year after diagnosis

Trial Locations

Locations (1)

the Sixth Affiliated Hospital of Sun Yat-Sen University; 🇨🇳 Guangzhou, Guangdong, China