Advantages and disadvantages of postmenopausal hormone therapy: a preventive trial - the Estonian Postmenopausal Hormone Therapy trial

Not Applicable

Completed

• Conditions: Menopausal disorders; Urological and Genital Diseases

• Registration Number: ISRCTN35338757
• Lead Sponsor: ational Research and Development Centre for Welfare and Health (STAKES) (Finland)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2004-10-15
• Last Update Posted: 28 November 2016

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 1823

Inclusion Criteria

1. Women aged 50 - 64 years
2. Last period at least 12 months before recruitment

Exclusion Criteria

Women with the following characteristics and health problems, as reported by women themselves or reported in patient records or health registers or found during the clinical examination are excluded from the study:
1. Current HT in last six months
2. Menstrual period within the last 12 months
3. Untreated endometrial adenomatosis or atypical hyperplasia of endometrium
4. Breast cancer, endometrial cancer, ovarian cancer
5. Any cancer treated less than 5 years ago
6. History of meningioma
7. Myocardial infarction within the last 6 months
8. History of hepatitis (not hepatitis A) or liver functional disorders during last 3 months
9. History of deep vein thrombosis, pulmonary embolism, cerebral infarction
10. Porphyria
11. Hypertension in spite of medication more than 170/110 mmHg
12. Endometriosis

Study & Design

• Study Type: Interventional
• Study Design: Not specified