ACTRN12621000563864已完成2 期
Effect of low dose atropine eye drops on ocular changes during accommodation in children and young adults with myopia
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 31
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 6 Years 至 25 Years（—）
- 性别
- All
入选标准
- •Healthy myopic children, adolescents, and young adults aged 6 to 25 years and with a myopic refractive error between -0.50 and -5.00 DS, and no greater than 1.00 D of astigmatism or anisometropia. Participants will currently be corrected with spectacles or contact lenses.
排除标准
- •Current or previous use of myopia control treatments (atropine, OrthoK, peripheral defocus soft contact lenses or spectacle lenses)
- •Amblyopia or strabismus
- •Stereopsis of 200 seconds of arc or greater
- •Monocular amplitude of accommodation of less than 8 D
- •Best corrected visual acuity (BCVA) poorer than 0.1 logMAR in both eyes, or greater than 1 line (0.1 logMAR) difference in VA between eyes
- •History of ocular surgery
- •History of significant ocular infection or injury
- •Known allergy to atropine, tropicamide, or benzalkonium chloride (BAK)
- •Known angle closure glaucoma, or temporal VH ratio <0.3:1 in either eye
- •Intraocular pressure greater than 21 mmHg in either eye
- •Current use of: anticholinergics, antiglaucoma medications, antimyasthenics, potassium drugs, carbachol/physostigmine/pilocarpine, no CNS depressants (such as antiemetics, phenothiazines, or barbiturates).
- •History of Down's syndrome, spastic paralysis, or brain damage.
研究者
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