The effect of single dose Nefopam on postoperative catheter-related bladder discomfort in patients undergoing transurethral resection of prostate: A randomized controlled trial
Phase 4
Recruiting
- Conditions
- catheter related bladder discomfortnormal saline 100 ml intravenous drip in 30 min
- Registration Number
- TCTR20191217005
- Lead Sponsor
- Faculty of Medicine, Khon Kaen University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
Patient undergoing Transurethral resection of prostate (TUR-P) under spinal anesthesia
ASA physical status class I-III
able to make decision and communicate
on urinary catheter traction at least 12 hours after operation
Exclusion Criteria
known allergic to nefopam or morphine
epilepsy
heart failure
arrhythmia
liver disease (total bilirubin>1.2 mg/dl AST>80 U/L ALT>66 U/L ALP>240 U/L)
Chronic kidney disease (GFR<60 ml/min/1.73 cm3)
current usage of monoamine oxidase inhibitor
drug abuse, alcoholism
acute closed angle glaucoma
morbid obesity (BMI>40 kg/m2)
psychological illness
chronic pain
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method degree of catheter-related bladder discomfort at 6 hour after operation patient report
- Secondary Outcome Measures
Name Time Method morphine consumption 24 hour after operation medical record