Antioxidant Capacity and Vitamin A Profile in Young Adults Who Consume a Snack Bar Made From Tropical Fruits Treated With UV-C
- Conditions
- Nutritional and Metabolic Disease
- Interventions
- Dietary Supplement: Pineapple snack barOther: No InterventionDietary Supplement: Mango snack bar
- Registration Number
- NCT03520725
- Brief Summary
The objective of the present study was to evaluate the impact of a snack bar on some health indicators associated with diet (plasma antioxidant capacity, lipid profile, vitamin A profile (retinol and carotenoids)) and on the nutritional status (impact on energy and nutrients consumed) in a group of upper level students.
- Detailed Description
A blind randomized controlled clinical study of healthy adults, which was carried out with the approval of the ethics committee of the Centro de Investigación en Alimentación y Desarrollo, A.C. (CIAD, A.C.) with registration CE/001/2017. The intervention was carried out in a public university in Mexico from January to April 2017. Each subject signed an informed consent form. This study lasted 30 days (4 weeks), where each participant consumed daily a snack bar irradiated with UV-C. The participants were personally interviewed by the research team with a structured selection questionnaire. Thirty subjects who met the inclusion criteria were recruited, 15 of them men and 15 women. Through a simple randomization process, the participants were assigned in 3 groups of 10 people each with 5 women and 5 men, subsequently treatments (without treatment, pineapple snack bar, or mango snack bar) were randomly assigned. The outcomes between groups were analyzed with one way ANOVA, with a P-value of 0.05 or less when there was statistical significance, using statistical software. The participants, and the laboratory technicians were blinded to the treatment assignments until the conclusion of the trial.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- Young adults of 18 years of age or older,
- Healthy in appearance
- People in current medical treatment
- Used antibiotics in past 15 days
- Have presented infectious symptoms on previous days
- Smokers
- Narcotic consumers
- Women in use of hormonal treatment
- Contraceptives or pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Intervention pineapple Pineapple snack bar Daily consumption of 30 g of pineapple snack bar for 4 weeks. No Intervention No Intervention This group did not have an intervention Intervention mango Mango snack bar Daily consumption of 30 g of mango snack bar for 4 weeks.
- Primary Outcome Measures
Name Time Method Change Oxygen Radical Absorbance Capacity Assay (Antioxidant Capacity) Change from baseline at thirty days From baseline and thirty days post treatment
Change Trolox Equivalent Antioxidant Capacity (Antioxidant Capacity) Change from baseline at thirty days From baseline and thirty days post treatment
Change Serum Retinol Determination Change from baseline at thirty days From baseline and thirty days post treatment
Change Serum pro-VA carotenoids Change from baseline at thirty days From baseline and thirty days post treatment
- Secondary Outcome Measures
Name Time Method Change Body composition by fat mass index Change from baseline at thirty days From baseline and thirty days post treatment
Change Body composition by fat-free mass index Change from baseline at thirty days From baseline and thirty days post treatment
Change Serum high density lipoprotein cholesterol Change from baseline at thirty days From baseline and thirty days post treatment
Change Serum total polyphenols determination Change from baseline at thirty days From baseline and thirty days post treatment
Change Serum cholesterol determination Change from baseline at thirty days From baseline and thirty days post treatment
Change Serum Triacylglycerides determination Change from baseline at thirty days From baseline and thirty days post treatment
Change Body Mass Index Change from baseline at thirty days From baseline and thirty days post treatment
24-hour dietary recall Baseline and thirty days From baseline and thirty days post treatment