Pain Relief and Functional Outcome After Partial Denervation of the Wrist

Not Applicable

Completed

• Conditions: Wrist Arthritis
• Interventions: Procedure: Partial denervation of the wrist joint

• Registration Number: NCT03378362
• Lead Sponsor: Karolinska Institutet

Brief Summary

Prospective study on the effect of partial wrist denervation (ie combined anterior and posterior interosseous neurectomy) on pain relief on functional outcome in patient with wrist osteoarthritis. The impact of psychological factors on postoperative outcome will be studied.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-12-13
• Study First Submitted QC: 2017-12-18
• Study First Posted: 2017-12-19
• Study Start: 2017-12-31
• Primary Completion: 2021-08-31
• Study Completion: 2021-08-31
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-28
• Last Update Posted: 2022-03-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Partial denervation of the wrist joint	Partial denervation of the wrist joint	Patients will be operated with a partial denervation of the wrist through a single dorsal approach.

Primary Outcome Measures

Name	Time	Method
Change in Disability of the Arm, Shoulder and Hand score (DASH)	peroperatively, 3, 6 and 12 months postoperatively	questionnaire

Secondary Outcome Measures

Name	Time	Method
Change in Hospital Anxiety and Depression Scale (HADS)	peroperatively, 3, 6 and 12 months postoperatively	questionnaire. Determines the levels of anxiety and depression. 14 item scale that generates ordinal data. Seven items relate to anxiety and seven to depression. Each item is scored from 0-3, which means that a person can score between 0-21 for either depression or anxiety. A score of 11 or above on either scale in considered to repressent depression or anxiety.
Change in range of motion, grip strength	peroperatively, 3, 6 and 12 months postoperatively	objective physical function
Change in EQ5D	peroperatively, 3, 6 and 12 months postoperatively	questionnaire
Change in Sence Of Coherence -13 (SOC13)	peroperatively, 3, 6 and 12 months postoperatively	Questionnaire
Change in Patient Related Wrist Evaluation (PRWE)	peroperatively, 3, 6 and 12 months postoperatively	questionnaire

Trial Locations

Locations (1)

Handkirurgiska kliniken Södersjukhuset; 🇸🇪 Stockholm, Sweden