Case Fatalities in Hospitalised COVID-19 Patients in the UK

Completed

• Conditions: Covid19
• Interventions: Other: Patient Characteristics; Other: COVID-19 treatments; Other: Differences in triage; Other: Surge capacity

• Registration Number: NCT04527458
• Lead Sponsor: University of Edinburgh

Brief Summary

This study will investigate how the case fatality in hospitalised patients with COVID-19 has changed throughout the pandemic. It will also explore possible mechanisms that could be driving these changes. This analysis will enhance our understanding of the virus, which will be important for researchers and clinicians to respond appropriately.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-02-24
• Status Verified: 2020-08
• Primary Completion: 2020-08-02
• Study Completion: 2020-08-02
• Study First Submitted: 2020-08-24
• Study First Submitted QC: 2020-08-24
• Last Update Submitted: 2020-08-24
• Study First Posted: 2020-08-26
• Last Update Posted: 2020-08-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70000

Inclusion Criteria

• All patients admitted with a proven or high likelihood of COVID-19

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Hospitalisations	Patient Characteristics	All hospitalised COVID patients
Hospitalisations	Differences in triage	All hospitalised COVID patients
Hospitalisations	COVID-19 treatments	All hospitalised COVID patients
Critical care	Surge capacity	All hospitalised COVID patients in critical care
Critical care	Patient Characteristics	All hospitalised COVID patients in critical care
Hospitalisations	Surge capacity	All hospitalised COVID patients
Critical care	COVID-19 treatments	All hospitalised COVID patients in critical care
Critical care	Differences in triage	All hospitalised COVID patients in critical care

Primary Outcome Measures

Name	Time	Method
Case fatality	23 weeks	The proportion of new admissions with COVID-19 who died over time

Trial Locations

Locations (1)

University of Edinburgh; 🇬🇧 Edinburgh, United Kingdom