临床试验/NCT02608164

NCT02608164已完成不适用

A Comparison of Capsules and Oral Spray Solution as Methods of Delivering Vitamin D3 and Raising Status: a Randomised Crossover Study

University of Ulster2 个研究点分布在 1 个国家目标入组 22 人开始时间: 2015年8月最近更新: 2016年5月26日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: University of Ulster
入组人数: 22
试验地点: 2
主要终点: Total 25-hydroxyvitamin D concentration

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The aim of the study is to compare the effectiveness of a vitamin D3 oral spray solution with capsules at raising vitamin D status over winter.

This randomised crossover trial will aim to recruit a total of 22 healthy participants for a total of two 4-week interventions separated by a 10-week washout.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Crossover
主要目的: Basic Science
盲法: None

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•Apparently healthy
•Over the age of 18

排除标准

•Those that intend to consume a supplement containing vitamin D at any point during the study
•Those under the age of
•Individuals that are on prescribed medication that is known to affect vitamin D metabolism
•Those following a vegan diet
•Sun-bed users
•Participants that are planning a sun holiday during the study

结局指标

主要结局

Total 25-hydroxyvitamin D concentration

时间窗: At baseline and weeks 4, 14 and 18

Total 25-hydroxyvitamin D concentration will be determined using liquid chromatography-tandem mass spectrometry in collected serum samples

次要结局

Biomarkers of vitamin D metabolism(At baseline and weeks 4, 14 and 18)
Dietary vitamin D intake(At week 18 only)

研究者

发起方

University of Ulster

申办方类型

Other

责任方

Principal Investigator

主要研究者

Dr Pamela Magee

University of Ulster

研究点 (2)

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