A comparative study of Polyethylene glycol 3350 and 4000 in the treatment of functional constipation in children aged 4-18 years:A randomised controlled trial

Dr SNIGDHA0 个研究点目标入组 90 人开始时间: 待定最近更新: 2023年7月25日

试验速览

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•Duration of more than 4 weeks for all ages .
•Presence of >=2 of the following :
•1) Defecation frequency <=2 times per week
•2) Fecal incontinence >=1 times per week after the acquisition of toileting skills ,
•3) history of excessive stool retention ( retentive posture, stool witholding behaviour)
•4) history of painful or hard bowel movements ,
•5) presence of a large mass in the rectum or on per abdomen examination
•6) history of large diameter stools that may obstruct the toilet.

•(Based on History , Physical Examination and Exclusion of Red Flags)
•1) Motility related disorders -Hirschprung disease
•2) Congenital anomalies -Anal stenosis , anteriorly displaced Anus,spinal cord anomalies( tethered cord , spina bifida)
•3) Devlopmental defect -mental retardation , autism OR cerebral palsy
•4) use of PEG with 2 months before inclusion or concurrent use of other drugs influencing gastrointestinal motility -opiates, anticholinergic agents,phenobarbitone,vincristine.

发起方

Dr SNIGDHA