The Role of Radiographic Indices in the Evaluation of Hand and Wrist Pathologies in Patients With Carpal Tunnel Syndrome
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 275
- Locations
- 1
- Primary Endpoint
- Measurement of Radiographic Indices
Study Overview
Brief Summary
The aim of this study was to compare wrist radiographic indices in patients with idiopathic carpal tunnel syndrome (CTS) with normal cases. The investigators believe that the investigators can contribute to the development of new treatment strategies by determining the radiographic features that contribute to the development of CTS.
Detailed Description
Carpal tunnel syndrome (CTS) is the most common mononeuropathy of the upper extremity. It occurs as a result of compression of the median nerve in the carpal tunnel during its course in the wrist. Clinical symptoms are characterized by numbness and tingling in the first 3 fingers and the radial half of the 4th finger, which are compatible with the distribution of the median nerve. Electrophysiologically, it is classified as mild, moderate and severe. As the disease duration increases, atrophy and weakness may develop in the thenar muscles. The incidence is 4-5% worldwide and is more common in women between the ages of 40-60.
Pathophysiology consists of mechanical compression, increased pressure, ischemia in the median nerve and local metabolic changes.
Among the risk factors, occupations that require repeated flexion and extension of the wrist constitute environmental risk factors. Extension can increase the tunnel pressure by 10 times, while flexion can increase it by more than 8 times. Systemic risk factors for CTS are pregnancy, menopause, obesity, renal failure, hypothyroidism, oral contraceptive use, and congestive heart failure.
Diabetes, alcoholism, vitamin deficiency or toxicity, and exposure to toxins are neuropathic risk factors. Localized risk factors include mass lesions that compress the tunnel, arthritis, and radius distal end fractures.
Despite these risk factors, most cases of CTS are still classified as idiopathic.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Not having had any previous surgical procedures on the hand or wrist
- •Not having had a major hand or wrist trauma
- •No structural disorders in the bone structure
Exclusion Criteria
- •Being under 18 years of age
- •History of major hand-wrist trauma or surgery
- •Acromegaly
- •Rheumatoid arthritis
- •Systemic lupus erythematosus
- •GUT arthritis
- •Psoriatic arthritis
Outcomes
Primary Outcomes
Measurement of Radiographic Indices
Time Frame: up to 12 weeks
Radio-lunate Angle (RLA): The distance between the tangential line connecting the two distal poles of the lunate root and the line drawn perpendicular to the central medullary canal of the distal radius.
Secondary Outcomes
- Boston Carpal Tunnel Syndrome Questionnaire(up to 12 weeks)
- Electromyography Examination(up to 12 weeks)
- Measurement of Radiographic Indices(up to 12 weeks)
Investigators
Nadide Koca
Principal Investigator
Ankara Training and Research Hospital