Screening of alpha thalassemia disease in Dubai by using red cell volume in cord blood.

Not Applicable

Recruiting

• Conditions: Alpha Thalassemia; Human Genetics and Inherited Disorders - Other human genetics and inherited disorders

• Registration Number: ACTRN12617000752369
• Lead Sponsor: dubai hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-05-22
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

All healthy neonates delivered at dubai hospital

Exclusion Criteria

1- major congenital anomalies
2- inpatient neonates underwent exchange transfusion.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the sensitivity of a low MCV on neonatal cord blood samples as a diagnostic tool of alpha thalassemia in Dubai by comparison to Hb electrophoresis and multiplex PCR results on each sample with MCV less than 90 Fl.[at birth]

Secondary Outcome Measures

Name	Time	Method
prevalence of neonatal alpha thalassemia syndrome in dubai by simultaneous testing of Hb electrophoresis, MCV, and multiplex PCR on neonatal cord blood samples.[at birth]