Comparison between effect of bispectral index and minimum alveolar anaesthetic concentration monitoring on recovery profile in patients undergoing general anesthesia

This study was conducted to investigate the effect of bispectral index (BIS) monitoring compared to the minimum alveolar anesthetic concentration (MAC) monitoring on recovery of patients undergoing isofluranebased general anesthesia. Materials and Methods: A total of 62 patients were randomly allocated to group B (BIS-guided) and group M (MAC-guided). Along with clinical hemodynamic monitoring for titration of isoflurane in group B, BIS was monitored and maintained between 40 and 60, whereas in group M, MAC was maintained between 0.7 and 1.3. The recovery profile was studied in terms of time to eye-opening, time to extubation, and time to achieve the modified Aldrete score ≥9 in both groups. Patients were followed up for any postoperative side effects and awareness during general anesthesia. Results: Group B and group M were comparable with respect to age, gender, duration of surgery, duration of anesthesia, and type of surgery. Median time to eye-opening was 4min in group B and 5min in group M (P < 0.001). The time to extubation was 8min in group B, compared to 11min in group M (P < 0.001). Furthermore, the time needed to achieve the modified Aldrete’s score of ≥9 was also shorter in group B (P < 0.001). No patients reported awareness during anesthesia.

Conclusion: The use of BIS monitoring hastens the extubation and recovery in patients undergoing general anesthesia