Differential Expression and Potential Value of c-MYC in Non-invasive and Invasive Mammary Carcinoma
Trial Snapshot
- Phase
- Not Applicable
- Status
- Enrolling By Invitation
- Sponsor
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- role of c-MYC in breast cancer
Study Overview
Brief Summary
Retrospective observational study to evaluate c-MYC expression in non invasive and invasive mammry carcinoma
Detailed Description
To correlate different levels of c-MYC expressions with variable clinical and pathological parameters of mammary carcinoma (such as patients' ages, tumor grading, staging, laterality, focality and nodal metastasis, co-existing in-situ components). This study will be carried out on archived formalin-fixed and paraffin embedded tissue blocks that were belonged to 70 women with breast lumps.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 15 Years to — (Child, Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Specimens of Modified Radical Mastectomies from breast carcinoma patients
Exclusion Criteria
- •Cases with insufficient clinical data.
- •Tissue blocks of destroyed or insufficient material, unfit for diagnosis.
- •Cases who received pre-operative chemotherapy.
Outcomes
Primary Outcomes
role of c-MYC in breast cancer
Time Frame: 1 year
difference between expression of c-MYC in non invasive and invasive mammary carcinoma
Secondary Outcomes
No secondary outcomes reported
Investigators
Marwa Mahmoud Hassan
resident doctor of pathologu
Sohag University
