The Effect of「GTT-EGCG」on Acne Women
Not Applicable
- Conditions
- Acne Lesion Counts
- Interventions
- Dietary Supplement: green tea extract EGCG
- Registration Number
- NCT01846338
- Lead Sponsor
- National Yang Ming Chiao Tung University
- Brief Summary
The aim of this study is to investigate the therapeutic effects of green tea extract on acne treatment and related hormone peptides by a double-blinded, randomized and controlled clinical trial.
- Detailed Description
change in acne lesions counts, hormone, quality of life
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
- Female patient
- 20 to 45 years of age
- moderate or severe acne vulgaris as defined by the Investigator's Global Assessment (IGA; score of 3 or 4 on a scale from 0 to 5)
Exclusion Criteria
- Received systemic retinoid or hormone treatment in the previous 3 months.
- Abnormal liver enzymes or kidney function tests (1.5 times higher than the upper normal limit)
- abnormal blood chemistry
- Pregnant or breast feeding women or the intention of becoming pregnant
- Concurrent systemic illness
- PCOS
- Very severe acne(IGA score5)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description green tea extract EGCG green tea extract EGCG experimental: green tea extract EGCG, 500mg , tid, 4 weeks cellulose green tea extract EGCG Placebo Comparator: cellulose, 500 mg tid, 4 weeks
- Primary Outcome Measures
Name Time Method acne lesion counts four weeks
- Secondary Outcome Measures
Name Time Method quality of life, SF-12 four weeks
Trial Locations
- Locations (1)
Taipei City Hospital
🇨🇳Taipei, Taiwan