Maintenance Transcranial Electrical Stimulation for Depression

Not Applicable

Completed

• Conditions: Bipolar Disorder; Major Depressive Disorder

• Registration Number: NCT01890356
• Lead Sponsor: The University of New South Wales

Brief Summary

Transcranial electrical stimulation (TES) techniques offer a novel treatment approach for depression and have shown promising efficacy. However, there is no published data to date on their effectiveness as a maintenance treatment. This study will investigate ways of using TES as a maintenance treatment to prevent relapse in depression.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-06
• Study First Submitted: 2013-06-26
• Study First Submitted QC: 2013-06-26
• Study First Posted: 2013-07-01
• Primary Completion: 2018-02
• Study Completion: 2018-02
• Status Verified: 2018-03
• Last Update Submitted: 2018-03-25
• Last Update Posted: 2018-03-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• All participants will be ≥ 18 years old.
• Participants must have experienced a significant clinical response, defined as ≥ 50% decrease from baseline scores on the Montgomery Asberg Depression Rating Scale (MADRS).

Exclusion Criteria

• Inadequate response to acute trial of TES.
• Suicidality.
• Clinically defined neurological disorder or insult.
• Metal in the cranium, skull defects, or skin lesions on scalp (cuts, abrasions, rash) at proposed electrode sites.
• Pregnancy (women of childbearing age will be asked to undergo a urine pregnancy test prior to starting the study).
• Concurrent long acting benzodiazepines, ritalin or dexamphetamine medication.
• Treatment for depression is changed during months 3-9 of the trial.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Montgomery Asberg Depression Rating Scale for Depression (MADRS)	9 months

Trial Locations

Locations (1)

Black Dog Institute / University of New South Wales; 🇦🇺 Randwick, Sydney, New South Wales, Australia

Black Dog Institute / University of New South Wales

🇦🇺Randwick, Sydney, New South Wales, Australia