Maintenance Transcranial Electrical Stimulation for Depression
Not Applicable
Completed
- Conditions
- Bipolar DisorderMajor Depressive Disorder
- Interventions
- Device: Transcranial electrical stimulation
- Registration Number
- NCT01890356
- Lead Sponsor
- The University of New South Wales
- Brief Summary
Transcranial electrical stimulation (TES) techniques offer a novel treatment approach for depression and have shown promising efficacy. However, there is no published data to date on their effectiveness as a maintenance treatment. This study will investigate ways of using TES as a maintenance treatment to prevent relapse in depression.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- All participants will be ≥ 18 years old.
- Participants must have experienced a significant clinical response, defined as ≥ 50% decrease from baseline scores on the Montgomery Asberg Depression Rating Scale (MADRS).
Exclusion Criteria
- Inadequate response to acute trial of TES.
- Suicidality.
- Clinically defined neurological disorder or insult.
- Metal in the cranium, skull defects, or skin lesions on scalp (cuts, abrasions, rash) at proposed electrode sites.
- Pregnancy (women of childbearing age will be asked to undergo a urine pregnancy test prior to starting the study).
- Concurrent long acting benzodiazepines, ritalin or dexamphetamine medication.
- Treatment for depression is changed during months 3-9 of the trial.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Transcranial electrical stimulation Transcranial electrical stimulation -
- Primary Outcome Measures
Name Time Method Montgomery Asberg Depression Rating Scale for Depression (MADRS) 9 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Black Dog Institute / University of New South Wales
🇦🇺Randwick, Sydney, New South Wales, Australia