Comparison of Pain Between Supraperiosteal Injection of Dexamethasone Versus Placebo on Postoperative Pain in Teeth With Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Post operative pain
研究概览
简要总结
This randomized controlled trial aims to compare the effectiveness of supra periosteal injection of dexamethasone versus placebo in reducing post operative pain in teeth diagnosed with symptomatic irreversible pulpitis. A total of 44 patients will be randomly assigned into two groups: Group A will receive a supra periosteal injection of dexamethasone(4mg/ml), and Group B will receive a similar injection of normal saline as placebo. post operative pain will be assessed at 6hr,24hr and 48hr using a VAS Analogue Scale, with the final outcome measured at 24hrs. the study will help determine whether local dexamethasone injection is effective in minimizing postoperative pain
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients age 18 or above 18 year old (to have complete apex formation)
- •Patient with normal periapical area (no pain on percussion).
- •Patient who have not received any preoperative analgesic and antibiotic in last one month.
排除标准
- •Pregnancy and Lactation because radiographs are contraindicated.
- •Moderate to severe periodontal disease because teeth are not salvageable.
- •Patient with nonvital teeth diagnose via cold test and EPT.
- •Patient with known sensitivity to dexamethasone by history.
- •Patients whose medical history include a history of certain illnesses, such as HIV, heart disease, or epilepsy (conditions that can affect a patient's rate of healing).
研究组 & 干预措施
Dexamethasone injection group
participant in this arm will receive a supraperiosteal injection of 4mg/ml dexamethasone at the mucobuccal fold prior to endodontic treatment for symptomatic irreversible pulpitis
干预措施: Dexamathsone 4mg/ml associated with experimental arm (Drug)
Saline injector(placebo) group
干预措施: Normal saline injection (Drug)
结局指标
主要结局
Post operative pain
时间窗: 24hr after endodontic treatment
Pain will be measured using a 10 - point Visual Analogue Scale where 0=no pain, 1-3=mild pain, 4-6= moderate pain, and 7-10 = severe pain the absence of pain will be considered as effective treatment
次要结局
未报告次要终点
研究者
Aqsa Afzal
AAfzal
College of Physicians and Surgeons Pakistan