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Acceptance & Tolerance Study of Multifocal Contact Lenses by Functional Emmetropes

Not Applicable
Completed
Conditions
Vision Correction
Interventions
Device: Multifocal Test Contact lens
Registration Number
NCT02394925
Lead Sponsor
Johnson & Johnson Vision Care, Inc.
Brief Summary

The primary objective of this study is to determine the retention rate over a two month period of vision correction in emmetropic, presbyopes fitted with multifocal contact lenses.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
113
Inclusion Criteria
  1. The subject must read, understand and sign the Statement of Informed Consent and receive a fully executed copy of the form.
  2. The subject must appear able and willing to adhere to the instructions set forth in this clinical protocol.
  3. The subject must be between 40 and 70 years of age.
  4. The subject's vertex corrected spherical equivalent distance refraction must be in the range of -1.00 to +2.00 in each eye.
  5. The subject's refractive cylinder must be less than or equal to -0.75 D in each eye.
  6. The subject's ADD power must be in the range of +0.75 D to +2.50.
  7. The subject must have best corrected visual acuity of 20/25 or better in each eye.
Exclusion Criteria
  1. Currently pregnant or lactating (subjects who become pregnant during the study will be discontinued).
  2. Any ocular or systemic allergies that contraindicate contact lens wear.
  3. Any ocular or systemic disease, autoimmune disease, or use of medication, that contraindicates contact lens wear.
  4. Any ocular abnormality that may interfere with contact lens wear.
  5. Use of any ocular medication, with the exception of rewetting drops.
  6. Any previous intraocular surgery (e.g. radial keratotomy, PRK, LASIK, etc.).
  7. Any grade 3 or greater slit lamp findings (e.g. edema, corneal neovascularization, corneal staining, tarsal abnormalities, conjunctival injection) which may contraindicate contact lens wear.
  8. History of herpetic keratitis.
  9. Any ocular infection or inflammation.
  10. Any corneal distortion or irregular cornea.
  11. History of binocular vision abnormality or strabismus.
  12. Any infectious disease (e.g. hepatitis, tuberculosis) or a contagious immunosuppressive disease (e.g. HIV).
  13. History of diabetes.
  14. Current or previous history of being prescribed a correction for distance vision.
  15. Current or previous history of contact lens wear.
  16. Participation in any contact lens or lens care product clinical trial within 30 days prior to study enrollment.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Multifocal Test Contact LensMultifocal Test Contact lensSubjects will wear the test lenses at least six hours per day, at least five days per week
Primary Outcome Measures
NameTimeMethod
Proportion of Successful Contact Lens Wearers2 months post wear

Proportion of Successful contact lens wearers is based on a subject's responses to two questionnaire items, "Overall Quality of Vision" and "Overall Comfort". Each item uses a 6 response like-rt scale (0= Not Applicable, 1=Excellent, 2=Very Good, 3=Good, 4=Fair and 5=Poor). The data from each item was dichotomized into two groups. If a subject responded "Excellent", "Very Good" or "Good" then the response=1, otherwise the response=0. The proportion of subjects with response=1 was reported as the proportion of successful contact lens wearers.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Tallahassee Eye Center

🇺🇸

Pensacola, Florida, United States

Ocular Technology Group-International

🇬🇧

London, United Kingdom

Tallahassee Eye Center
🇺🇸Pensacola, Florida, United States
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